这是用户在 2024-7-24 11:56 为 https://pubmed.ncbi.nlm.nih.gov/?term=(PHF6%5BTitle%5D)&filter=simsearch2.ffrft&sort=date&size=50 保存的双语快照页面，由 沉浸式翻译 提供双语支持。了解如何保存？
Skip to main page content
U.S. flag

An official website of the United States government

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters 我的ncbi过滤器

Results by year  各年结果

2003
2024

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2004 1
2005 2
2006 2
2007 1
2010 3
2011 3
2012 1
2013 2
2014 2
2015 7
2016 4
2017 2
2018 4
2019 11
2020 5
2021 13
2022 8
2023 8
2024 6
easyScholar显示设置

Text availability  文本可用性

Article attribute  商品属性

Article type  文章类型

Publication date  出版日期

Search Results

75 results

Results by year

Filters applied: Free full text. Clear all
应用的过滤器：免费全文。清除所有
Page 1 第1页
Investigating the physiological role of S199A and S199D mutants of PHF6 protein in T-cell acute lymphoblastic leukemia.
探讨PHF6蛋白S199A和S199D突变在T细胞急性淋巴细胞白血病中的生理作用。 Turkish Journal of Medical SciencesSCI升级版 医学4区SCI基础版 医学4区IF 1.2
Erdoğan G, Özeş ON, Küpesiz A, Yoldaş ŞB. Erdoğan G, et al. Turk J Med Sci. 2023 Aug 11;53(5):1234-1243. doi: 10.55730/1300-0144.5689. eCollection 2023. Turk J Med Sci. 2023. PMID: 38812997 Free PMC article.
Exploring the Aggregation Propensity of PHF6 Peptide Segments of the Tau Protein Using Ion Mobility Mass Spectrometry Techniques.
利用离子迁移质谱技术探索Tau蛋白PHF6多肽片段的聚集倾向。 Analytical Chemistry化学TOPEI检索SCI升级版 化学1区SCI基础版 化学2区IF 6.7
Stroganova I, Willenberg H, Tente T, Depraz Depland A, Bakels S, Rijs AM. Stroganova I, et al. Anal Chem. 2024 Apr 2;96(13):5115-5124. doi: 10.1021/acs.analchem.3c04974. Epub 2024 Mar 22. Anal Chem. 2024. PMID: 38517679 Free PMC article.
A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein.
针对tau固有无序蛋白中PHF6线性多肽的单域抗体的选择和优化策略。 The Journal of Biological Chemistry生物学TOPEI检索SCI升级版 生物学2区SCI基础版 生物2区IF 4.0
Mortelecque J, Zejneli O, Bégard S, Simões MC, ElHajjar L, Nguyen M, Cantrelle FX, Hanoulle X, Rain JC, Colin M, Gomes CM, Buée L, Landrieu I, Danis C, Dupré E. Mortelecque J, et al. J Biol Chem. 2024 Apr;300(4):107163. doi: 10.1016/j.jbc.2024.107163. Epub 2024 Mar 12. J Biol Chem. 2024. PMID: 38484799 Free PMC article.
PHF6-mediated transcriptional control of NSC via Ephrin receptors is impaired in the intellectual disability syndrome BFLS.
在智能障碍综合征BFLS中，PHF6通过Ephin受体介导的NSC转录调控受损。 Embo Reports生物学TOPSCI升级版 生物学1区SCI基础版 生物1区IF 6.5
Rasool D, Burban A, Sharanek A, Madrigal A, Hu J, Yan K, Qu D, Voss AK, Slack RS, Thomas T, Bonni A, Picketts DJ, Soleimani VD, Najafabadi HS, Jahani-Asl A. Rasool D, et al. EMBO Rep. 2024 Mar;25(3):1256-1281. doi: 10.1038/s44319-024-00082-0. Epub 2024 Mar 1. EMBO Rep. 2024. PMID: 38429579 Free PMC article.
Molecular and clinical analyses of PHF6 mutant myeloid neoplasia provide their pathogenesis and therapeutic targeting.
PHF 6突变型骨髓瘤变的分子和临床分析提供了其发病机制和治疗靶向。 Nature Communications综合性期刊TOPSCI升级版 综合性期刊1区SCI基础版 综合性期刊1区IF 14.7
Kubota Y, Gu X, Terkawi L, Bodo J, Przychodzen BP, Awada H, Williams N, Gurnari C, Kawashima N, Aly M, Durmaz A, Mori M, Ponvilawan B, Kewan T, Bahaj W, Meggendorfer M, Jha BK, Visconte V, Rogers HJ, Haferlach T, Maciejewski JP. Kubota Y, et al. Nat Commun. 2024 Feb 28;15(1):1832. doi: 10.1038/s41467-024-46134-w. Nat Commun. 2024. PMID: 38418452 Free PMC article.
PHF6 loss reduces leukemia stem cell activity in an acute myeloid leukemia mouse model.
PHF 6缺失降低了急性骨髓性白血病小鼠模型中的白血病干细胞活性。 Cancer Cell InternationalSCI升级版 医学2区SCI基础版 医学2区IF 5.3
Yuan S, Gao M, Wang Y, Lan Y, Li M, Du Y, Li Y, Ju W, Huang Y, Yuan K, Zeng L. Yuan S, et al. Cancer Cell Int. 2024 Feb 9;24(1):66. doi: 10.1186/s12935-024-03265-w. Cancer Cell Int. 2024. PMID: 38336746 Free PMC article.
PHF6 suppresses self-renewal of leukemic stem cells in AML.
PHF6抑制AML中白血病干细胞的自我更新。 Biorxiv [Preprint] Biorxiv [预印本]
Jalnapurkar SS, Pawar A, George SS, Antony C, Grana J, Gurbuxani S, Paralkar VR. Jalnapurkar SS, et al. bioRxiv [Preprint]. 2024 Jan 18:2024.01.06.573649. doi: 10.1101/2024.01.06.573649. bioRxiv. 2024. Update in: Leukemia. 2024 Jul 14. doi: 10.1038/s41375-024-02340-5. PMID: 38260439 Free PMC article. Updated. Preprint.
Mapping the configurational landscape and aggregation phase behavior of the tau protein fragment PHF6.
绘制tau蛋白片段PHF6的构型景观和聚集相行为。 Proceedings of The National Academy of Sciences of The United States of America综合性期刊TOPSCI升级版 综合性期刊1区SCI基础版 综合性期刊1区IF 9.4
Pretti E, Shell MS. Pretti E, et al. Proc Natl Acad Sci U S A. 2023 Nov 28;120(48):e2309995120. doi: 10.1073/pnas.2309995120. Epub 2023 Nov 20. Proc Natl Acad Sci U S A. 2023. PMID: 37983502 Free PMC article.
PHF6 maintains acute myeloid leukemia via regulating NF-kappaB signaling pathway.
PHF 6通过调节NF-kappaB信号途径维持急性骨髓性白血病。 Leukemia医学TOPSCI升级版 医学1区SCI基础版 医学1区IF 12.8
Hou S, Wang X, Guo T, Lan Y, Yuan S, Yang S, Zhao F, Fang A, Liu N, Yang W, Chu Y, Jiang E, Cheng T, Sun X, Yuan W. Hou S, et al. Leukemia. 2023 Aug;37(8):1626-1637. doi: 10.1038/s41375-023-01953-6. Epub 2023 Jul 1. Leukemia. 2023. PMID: 37393343 Free PMC article.
R274X-mutated Phf6 increased the self-renewal and skewed T cell differentiation of hematopoietic stem cells.
R274X突变的Phf6增加了造血干细胞的自我更新和偏向T细胞分化。 IscienceSCI升级版 综合性期刊2区SCI基础版 综合性期刊2区IF 4.6
Lan Y, Yuan S, Guo T, Hou S, Zhao F, Yang W, Cao Y, Chu Y, Jiang E, Yuan W, Wang X. Lan Y, et al. iScience. 2023 May 5;26(6):106817. doi: 10.1016/j.isci.2023.106817. eCollection 2023 Jun 16. iScience. 2023. PMID: 37288345 Free PMC article.
Long noncoding RNA Bmp1 modulates PHF6 expression by sponging miR-128-3p to protect intestinal mucosal in burned mice.
长非编码RNA Bmp1通过海绵miR-128-3p调节PHF6的表达，以保护烧伤小鼠肠黏膜。 Asian Journal of SurgerySCI升级版 医学3区SCI基础版 医学3区IF 3.5
Zhuang M, Yan H, Li Q, Sun Y. Zhuang M, et al. Asian J Surg. 2023 Aug;46(8):3116-3117. doi: 10.1016/j.asjsur.2023.02.075. Epub 2023 Mar 4. Asian J Surg. 2023. PMID: 36878784 Free article. No abstract available.
PHF6 promotes the progression of endometrial carcinoma by increasing cancer cells growth and decreasing T-cell infiltration.
PHF6通过促进癌细胞生长和减少T细胞的浸润而促进子宫内膜癌的进展。 Journal of Cellular And Molecular Medicine医学TOPSCI升级版 医学2区SCI基础版 医学2区IF 4.3
Wang X, Fang A, Peng Y, Yu J, Yu C, Xie J, Zheng Y, Song L, Li P, Li J, Kang X, Lin Y, Li W. Wang X, et al. J Cell Mol Med. 2023 Mar;27(5):609-621. doi: 10.1111/jcmm.17638. Epub 2023 Feb 8. J Cell Mol Med. 2023. PMID: 36756714 Free PMC article.
Concurrent Mutations in SF3B1 and PHF6 in Myeloid Neoplasms.
髓系肿瘤中SF3B1和PHF6的同时突变 Biology-baselSCI升级版 生物学3区SCI基础版 生物2区IF 3.6
Zuo Z, Medeiros LJ, Garces S, Routbort MJ, Ok CY, Loghavi S, Kanagal-Shamanna R, Jelloul FZ, Garcia-Manero G, Chien KS, Patel KP, Luthra R, Yin CC. Zuo Z, et al. Biology (Basel). 2022 Dec 21;12(1):13. doi: 10.3390/biology12010013. Biology (Basel). 2022. PMID: 36671709 Free PMC article.
PHF6 functions as a tumor suppressor by recruiting methyltransferase SUV39H1 to nucleolar region and offers a novel therapeutic target for PHF6-muntant leukemia.
PHF6通过将甲基转移酶SUV39H1募集到核仁区而发挥肿瘤抑制作用，为PHF6-Munant白血病提供了一个新的治疗靶点。 Acta Pharmaceutica Sinica b医学TOPSCI升级版 医学1区SCI基础版 医学1区IF 14.7
Tsai HI, Wu Y, Huang R, Su D, Wu Y, Liu X, Wang L, Xu Z, Pang Y, Sun C, He C, Shu F, Zhu H, Wang D, Cheng F, Huang L, Chen H. Tsai HI, et al. Acta Pharm Sin B. 2022 Apr;12(4):1913-1927. doi: 10.1016/j.apsb.2021.10.025. Epub 2021 Oct 30. Acta Pharm Sin B. 2022. PMID: 35847518 Free PMC article.
Further characterization of Borjeson-Forssman-Lehmann syndrome in females due to de novo variants in PHF6.
PHF6基因从头变异导致女性Borjeson-Forssman-Lehmann综合征的进一步特征。 Clinical GeneticsSCI升级版 医学3区SCI基础版 医学2区IF 2.9
Gerber CB, Fliedner A, Bartsch O, Berland S, Dewenter M, Haug M, Hayes I, Marin-Reina P, Mark PR, Martinez-Castellano F, Maystadt I, Karadurmus D, Steindl K, Wiesener A, Zweier M, Sticht H, Zweier C. Gerber CB, et al. Clin Genet. 2022 Sep;102(3):182-190. doi: 10.1111/cge.14173. Epub 2022 Jun 14. Clin Genet. 2022. PMID: 35662002 Free PMC article.
Functional mapping of PHF6 complexes in chromatin remodeling, replication dynamics, and DNA repair.
PHF 6复合物在染色质重塑、复制动力学和DNA修复中的功能绘图。 Blood医学TOPSCI升级版 医学1区SCI基础版 医学1区IF 21.0
Alvarez S, da Silva Almeida AC, Albero R, Biswas M, Barreto-Galvez A, Gunning TS, Shaikh A, Aparicio T, Wendorff A, Piovan E, Van Vlierberghe P, Gygi S, Gautier J, Madireddy A, A Ferrando A. Alvarez S, et al. Blood. 2022 Jun 9;139(23):3418-3429. doi: 10.1182/blood.2021014103. Blood. 2022. PMID: 35338774 Free PMC article.
Effect of Trehalose and Ceftriaxone on the Stability of Aggregating-Prone Tau Peptide Containing PHF6* Sequence: An SRCD Study.
海藻糖和头孢曲松对含有PHF6*序列的易聚集Tau多肽稳定性的影响：一项SRCD研究。 International Journal of Molecular SciencesSCI升级版 生物学2区SCI基础版 生物2区IF 4.9
Honisch C, Torni F, Hussain R, Ruzza P, Siligardi G. Honisch C, et al. Int J Mol Sci. 2022 Mar 8;23(6):2932. doi: 10.3390/ijms23062932. Int J Mol Sci. 2022. PMID: 35328353 Free PMC article.
Silva O, Kurzer J. Nonleukemic T/B mixed phenotype acute leukemia with PHF6 and NOTCH1 mutations. Blood. 2021;138(9):818.
Silva O、Kurzer J.非白血病T/B混合表型急性白血病，伴有PHF 6和NOTCH 1突变。血2021;138（9）：818。 Blood医学TOPSCI升级版 医学1区SCI基础版 医学1区IF 21.0
[No authors listed] [No authors listed] Blood. 2022 Mar 10;139(10):1602. doi: 10.1182/blood.2022015719. Blood. 2022. PMID: 35267002 Free article. No abstract available.
LINC00958/miR-3174/PHF6 axis is responsible for triggering proliferation, migration and invasion of endometrial cancer.
LINC00958/miR-3174/PHF6轴与子宫内膜癌的增殖、迁移和侵袭有关。 European Review For Medical And Pharmacological SciencesSCI升级版 医学4区SCI基础版 医学3区
欧洲医学和药理学评论SCI升级版医学4区SCI基础版医学3区
Li QY, Shen JQ, Li JH, Dai DF, Saeed M, Li CX. Li QY, et al. Eur Rev Med Pharmacol Sci. 2021 Nov;25(22):6853-6861. doi: 10.26355/eurrev_202111_27233. Eur Rev Med Pharmacol Sci. 2021. PMID: 34859848 Free article.
Gene body methylation safeguards ribosomal DNA transcription by preventing PHF6-mediated enrichment of repressive histone mark H4K20me3.
基因体甲基化通过阻止PHF6介导的抑制性组蛋白标记H4K20me3的浓缩来保护核糖体DNA转录。 The Journal of Biological Chemistry生物学TOPEI检索SCI升级版 生物学2区SCI基础版 生物2区IF 4.0
Huang X, Zhang X, Zong L, Gao Q, Zhang C, Wei R, Guan Y, Huang L, Zhang L, Lyu G, Tao W. Huang X, et al. J Biol Chem. 2021 Oct;297(4):101195. doi: 10.1016/j.jbc.2021.101195. Epub 2021 Sep 11. J Biol Chem. 2021. PMID: 34520760 Free PMC article.
Effects of All-Atom Molecular Mechanics Force Fields on Amyloid Peptide Assembly: The Case of PHF6 Peptide of Tau Protein.
全原子分子力力场对淀粉样多肽组装的影响：以Tau蛋白PHF6多肽为例。 Journal of Chemical Theory And Computation化学TOPSCI升级版 化学1区SCI基础版 化学2区IF 5.7
Man VH, He X, Gao J, Wang J. Man VH, et al. J Chem Theory Comput. 2021 Oct 12;17(10):6458-6471. doi: 10.1021/acs.jctc.1c00028. Epub 2021 Sep 7. J Chem Theory Comput. 2021. PMID: 34491058 Free PMC article.
PHF6 and JAK3 mutations cooperate to drive T-cell acute lymphoblastic leukemia progression.
PHF 6和JAK 3突变共同推动T细胞急性淋巴细胞白血病进展。 Leukemia医学TOPSCI升级版 医学1区SCI基础版 医学1区IF 12.8
Yuan S, Wang X, Hou S, Guo T, Lan Y, Yang S, Zhao F, Gao J, Wang Y, Chu Y, Shi J, Cheng T, Yuan W. Yuan S, et al. Leukemia. 2022 Feb;36(2):370-382. doi: 10.1038/s41375-021-01392-1. Epub 2021 Aug 31. Leukemia. 2022. PMID: 34465864 Free PMC article.
Aggregated Tau-PHF6 (VQIVYK) Potentiates NLRP3 Inflammasome Expression and Autophagy in Human Microglial Cells.
聚集的Tau-PHF6(VQIVYK)增强NLRP3在人小胶质细胞中的炎症体表达和自噬。 CellsSCI升级版 生物学2区SCI基础版 生物2区IF 5.1
Panda C, Voelz C, Habib P, Mevissen C, Pufe T, Beyer C, Gupta S, Slowik A. Panda C, et al. Cells. 2021 Jun 30;10(7):1652. doi: 10.3390/cells10071652. Cells. 2021. PMID: 34209408 Free PMC article.
LncRNA Bmp1 promotes the healing of intestinal mucosal lesions via the miR-128-3p/PHF6/PI3K/AKT pathway.
LncRNA Bmp1通过miR-128-3p/PHF6/PI3K/AKT通路促进肠粘膜损伤的修复。 Cell Death & Disease生物学TOPSCI升级版 生物学1区SCI基础版 生物2区IF 8.1
Zhuang M, Deng Y, Zhang W, Zhu B, Yan H, Lou J, Zhang P, Cui Q, Tang H, Sun H, Sun Y. Zhuang M, et al. Cell Death Dis. 2021 Jun 9;12(6):595. doi: 10.1038/s41419-021-03879-2. Cell Death Dis. 2021. PMID: 34108447 Free PMC article.
Transgenic mice with an R342X mutation in Phf6 display clinical features of Borjeson-Forssman-Lehmann Syndrome.
带有Phf6基因R342X突变的转基因小鼠表现出Borjeson-Forssman-Lehmann综合征的临床特征。 Human Molecular GeneticsSCI升级版 生物学2区SCI基础版 生物2区IF 3.1
Ahmed R, Sarwar S, Hu J, Cardin V, Qiu LR, Zapata G, Vandeleur L, Yan K, Lerch JP, Corbett MA, Gecz J, Picketts DJ. Ahmed R, et al. Hum Mol Genet. 2021 May 12;30(7):575-594. doi: 10.1093/hmg/ddab081. Hum Mol Genet. 2021. PMID: 33772537 Free PMC article.
Notoginsenoside R1 induces DNA damage via PHF6 protein to inhibit cervical carcinoma cell proliferation.
Notocumab R1通过PHF 6蛋白诱导DNA损伤，抑制宫颈癌细胞的生长。 Molecular Medicine ReportsSCI升级版 医学3区SCI基础版 医学4区IF 3.4
Cai T, Wu W, Guo L, Xia Y, Jiang X, Zhang L, Peng F, Ming P. Cai T, et al. Mol Med Rep. 2021 Apr;23(4):242. doi: 10.3892/mmr.2021.11881. Epub 2021 Feb 4. Mol Med Rep. 2021. PMID: 33537816 Free PMC article.
PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation.
PHF6表达水平影响人类造血干细胞分化。 Frontiers in Cell And Developmental BiologySCI升级版 生物学2区SCI基础版 生物2区IF 4.6
Loontiens S, Dolens AC, Strubbe S, Van de Walle I, Moore FE, Depestel L, Vanhauwaert S, Matthijssens F, Langenau DM, Speleman F, Van Vlierberghe P, Durinck K, Taghon T. Loontiens S, et al. Front Cell Dev Biol. 2020 Nov 4;8:599472. doi: 10.3389/fcell.2020.599472. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33251223 Free PMC article.
The chromatin-binding protein PHF6 functions as an E3 ubiquitin ligase of H2BK120 via H2BK12Ac recognition for activation of trophectodermal genes.
染色质结合蛋白PHF 6作为H2 BK 120的E3遍在蛋白连接酶，通过H2 BK 12 Ab识别激活滋养外胚基因。 Nucleic Acids Research生物学TOPSCI升级版 生物学2区SCI基础版 生物1区IF 16.6
Oh S, Boo K, Kim J, Baek SA, Jeon Y, You J, Lee H, Choi HJ, Park D, Lee JM, Baek SH. Oh S, et al. Nucleic Acids Res. 2020 Sep 18;48(16):9037-9052. doi: 10.1093/nar/gkaa626. Nucleic Acids Res. 2020. PMID: 32735658 Free PMC article.
Chromatin-Binding Protein PHF6 Regulates Activity-Dependent Transcriptional Networks to Promote Hunger Response.
染色质结合蛋白PHF6调节活性依赖的转录网络以促进饥饿反应。 Cell Reports生物学TOPSCI升级版 生物学1区SCI基础版 生物1区IF 7.5
Gan L, Sun J, Yang S, Zhang X, Chen W, Sun Y, Wu X, Cheng C, Yuan J, Li A, Corbett MA, Dixon MP, Thomas T, Voss AK, Gécz J, Wang GZ, Bonni A, Li Q, Huang J. Gan L, et al. Cell Rep. 2020 Mar 17;30(11):3717-3728.e6. doi: 10.1016/j.celrep.2020.02.085. Cell Rep. 2020. PMID: 32187544 Free article.
PHF6 promotes non-homologous end joining and G2 checkpoint recovery.
PHF6可促进非同源末端连接和G2检查点恢复。 Embo Reports生物学TOPSCI升级版 生物学1区SCI基础版 生物1区IF 6.5
Warmerdam DO, Alonso-de Vega I, Wiegant WW, van den Broek B, Rother MB, Wolthuis RM, Freire R, van Attikum H, Medema RH, Smits VA. Warmerdam DO, et al. EMBO Rep. 2020 Jan 7;21(1):e48460. doi: 10.15252/embr.201948460. Epub 2019 Nov 29. EMBO Rep. 2020. PMID: 31782600 Free PMC article.
Phf6-null hematopoietic stem cells have enhanced self-renewal capacity and oncogenic potentials.
Phf 6缺失的骨髓干细胞具有增强的自我更新能力和致癌潜力。 Blood Advances医学TOPSCI升级版 医学1区SCI基础版 医学2区IF 7.4
Hsu YC, Chen TC, Lin CC, Yuan CT, Hsu CL, Hou HA, Kao CJ, Chuang PH, Chen YR, Chou WC, Tien HF. Hsu YC, et al. Blood Adv. 2019 Aug 13;3(15):2355-2367. doi: 10.1182/bloodadvances.2019000391. Blood Adv. 2019. PMID: 31395598 Free PMC article.
Xiao W, Bharadwaj M, Levine M, et al. PHF6 and DNMT3A mutations are enriched in distinct subgroups of mixed phenotype acute leukemia with T-lineage differentiation. Blood Adv. 2018;2(23):3526-3539.
Xao W、Bharadwaj M、Levine M等。PHF 6和DNMT 3A突变在具有T谱系分化的混合表型急性白血病的不同亚组中富集。Blood Adv. 2018;2（23）：3526-3539。 Blood Advances医学TOPSCI升级版 医学1区SCI基础版 医学2区IF 7.4
[No authors listed] [No authors listed] Blood Adv. 2019 Apr 9;3(7):956. doi: 10.1182/bloodadvances.2019033076. Blood Adv. 2019. PMID: 30926597 Free PMC article. No abstract available.
The chromatin-binding protein Phf6 restricts the self-renewal of hematopoietic stem cells.
染色质结合蛋白Phf6限制了造血干细胞的自我更新。 Blood医学TOPSCI升级版 医学1区SCI基础版 医学1区IF 21.0
Miyagi S, Sroczynska P, Kato Y, Nakajima-Takagi Y, Oshima M, Rizq O, Takayama N, Saraya A, Mizuno S, Sugiyama F, Takahashi S, Matsuzaki Y, Christensen J, Helin K, Iwama A. Miyagi S, et al. Blood. 2019 Jun 6;133(23):2495-2506. doi: 10.1182/blood.2019000468. Epub 2019 Mar 27. Blood. 2019. PMID: 30917958 Free article.
PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia.
PHF6调节造血干/祖细胞，其缺失与TLX3的表达协同作用，导致白血病的发生。 Blood医学TOPSCI升级版 医学1区SCI基础版 医学1区IF 21.0
McRae HM, Garnham AL, Hu Y, Witkowski MT, Corbett MA, Dixon MP, May RE, Sheikh BN, Chiang W, Kueh AJ, Nguyen TA, Man K, Gloury R, Aubrey BJ, Policheni A, Di Rago L, Alexander WS, Gray DHD, Strasser A, Hawkins ED, Wilcox S, Gécz J, Kallies A, McCormack MP, Smyth GK, Voss AK, Thomas T. McRae HM, et al. Blood. 2019 Apr 18;133(16):1729-1741. doi: 10.1182/blood-2018-07-860726. Epub 2019 Feb 12. Blood. 2019. PMID: 30755422 Free PMC article.
A Novel Nonsense Mutation of PHF6 in a Female with Extended Phenotypes of Borjeson-Forssman-Lehmann Syndrome.
一名具有博耶森-福斯曼-莱曼综合征扩展表型的女性中PHF 6的新型无意义突变。 Journal of Clinical Research in Pediatric EndocrinologySCI升级版 医学4区SCI基础版 医学4区IF 1.5
儿科内分泌临床研究杂志SCI升级版医学4区SCI基础版医学4区IF 1.5
Zhang X, Fan Y, Liu X, Zhu MA, Sun Y, Yan H, He Y, Ye X, Gu X, Yu Y. Zhang X, et al. J Clin Res Pediatr Endocrinol. 2019 Nov 22;11(4):419-425. doi: 10.4274/jcrpe.galenos.2019.2018.0220. Epub 2019 Jan 11. J Clin Res Pediatr Endocrinol. 2019. PMID: 30630810 Free PMC article.
Phf6 Loss Enhances HSC Self-Renewal Driving Tumor Initiation and Leukemia Stem Cell Activity in T-ALL.
Phf 6缺失增强了RSC自我更新，推动T-ALL中的肿瘤发生和白血病干细胞活性。 Cancer Discovery医学TOPSCI升级版 医学1区SCI基础版 医学1区IF 29.7
Wendorff AA, Quinn SA, Rashkovan M, Madubata CJ, Ambesi-Impiombato A, Litzow MR, Tallman MS, Paietta E, Paganin M, Basso G, Gastier-Foster JM, Loh ML, Rabadan R, Van Vlierberghe P, Ferrando AA. Wendorff AA, et al. Cancer Discov. 2019 Mar;9(3):436-451. doi: 10.1158/2159-8290.CD-18-1005. Epub 2018 Dec 19. Cancer Discov. 2019. PMID: 30567843 Free PMC article.
The depletion of PHF6 decreases the drug sensitivity of T-cell acute lymphoblastic leukemia to prednisolone.
PHF 6的耗尽降低了T细胞急性淋巴细胞白血病对泼尼龙的药物敏感性。 Biomedicine & Pharmacotherapy医学TOPSCI升级版 医学2区SCI基础版 医学2区IF 6.9
Xiang J, Wang G, Xia T, Chen Z. Xiang J, et al. Biomed Pharmacother. 2019 Jan;109:2210-2217. doi: 10.1016/j.biopha.2018.11.083. Epub 2018 Nov 28. Biomed Pharmacother. 2019. PMID: 30551478 Free article.
PHF6 and DNMT3A mutations are enriched in distinct subgroups of mixed phenotype acute leukemia with T-lineage differentiation.
PHF6和DNMT3A突变在具有T系分化的混合表型急性白血病的不同亚群中丰富。 Blood Advances医学TOPSCI升级版 医学1区SCI基础版 医学2区IF 7.4
Xiao W, Bharadwaj M, Levine M, Farnhoud N, Pastore F, Getta BM, Hultquist A, Famulare C, Medina JS, Patel MA, Gao Q, Lewis N, Pichardo J, Baik J, Shaffer B, Giralt S, Rampal R, Devlin S, Cimera R, Zhang Y, E Arcila M, Papaemmanuil E, Levine RL, Roshal M. Xiao W, et al. Blood Adv. 2018 Dec 11;2(23):3526-3539. doi: 10.1182/bloodadvances.2018023531. Blood Adv. 2018. PMID: 30530780 Free PMC article.
Mechanistic insights into remodeled Tau-derived PHF6 peptide fibrils by Naphthoquinone-Tryptophan hybrids.
通过萘醌-色氨酸杂交物对牛磺酸衍生的PHF6多肽原纤维进行重塑的机制洞察。 Scientific ReportsSCI升级版 综合性期刊2区SCI基础版 综合性期刊3区IF 3.8
KrishnaKumar VG, Paul A, Gazit E, Segal D. KrishnaKumar VG, et al. Sci Rep. 2018 Jan 8;8(1):71. doi: 10.1038/s41598-017-18443-2. Sci Rep. 2018. PMID: 29311706 Free PMC article.
Coexistence of EZH2, NOTCH1, IL7R, and PHF6 Mutations in Adult T-cell Acute Lymphoblastic Leukemia.
成人T细胞急性淋巴细胞白血病中EZH2、NOTCH1、IL7R和PHF6突变的共存 Turkish Journal of HematologySCI升级版 医学4区SCI基础版 医学4区IF 1.5
Zhou X, Gu Y, Han Q, Soliman M, Song C, Ge Z. Zhou X, et al. Turk J Haematol. 2017 Dec 1;34(4):366-368. doi: 10.4274/tjh.2017.0194. Epub 2017 Jul 27. Turk J Haematol. 2017. PMID: 28747286 Free PMC article. No abstract available.
Page 2 第2页
PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes.
PHF 6通过谱系特异性基因内的染色质组织调节表型可塑性。 Genes & Development生物学TOPSCI升级版 生物学1区SCI基础版 生物1区IF 7.5
Soto-Feliciano YM, Bartlebaugh JME, Liu Y, Sánchez-Rivera FJ, Bhutkar A, Weintraub AS, Buenrostro JD, Cheng CS, Regev A, Jacks TE, Young RA, Hemann MT. Soto-Feliciano YM, et al. Genes Dev. 2017 May 15;31(10):973-989. doi: 10.1101/gad.295857.117. Epub 2017 Jun 12. Genes Dev. 2017. PMID: 28607179 Free PMC article.
PHF6 mutations in paediatric acute myeloid leukaemia.
儿科急性骨髓性白血病中的PHF 6突变。 British Journal of Haematology医学TOPSCI升级版 医学2区SCI基础版 医学2区IF 5.1
de Rooij JD, van den Heuvel-Eibrink MM, van de Rijdt NK, Verboon LJ, de Haas V, Trka J, Baruchel A, Reinhardt D, Pieters R, Fornerod M, Zwaan CM. de Rooij JD, et al. Br J Haematol. 2016 Dec;175(5):967-971. doi: 10.1111/bjh.13891. Epub 2015 Dec 21. Br J Haematol. 2016. PMID: 27885656 Free article. No abstract available.
The sub-nucleolar localization of PHF6 defines its role in rDNA transcription and early processing events. European Journal of Human GeneticsSCI升级版 生物学2区SCI基础版 生物3区IF 3.7
PHF 6的亚核仁定位定义了其在TLR转录和早期加工事件中的作用。欧洲人类遗传学杂志SCI升级版生物学2区SCI基础版生物3区IF 3.7
Todd MA, Huh MS, Picketts DJ. Todd MA, et al. Eur J Hum Genet. 2016 Oct;24(10):1453-9. doi: 10.1038/ejhg.2016.40. Epub 2016 May 11. Eur J Hum Genet. 2016. PMID: 27165002 Free PMC article.
The PHF6 Mutation c.1A>G; pM1V Causes Borjeson-Forsman-Lehmann Syndrome in a Family with Four Affected Young Boys. Molecular SyndromologySCI升级版 医学4区SCI基础版 医学4区IF 0.9
PHF 6突变c.1A>G; pM 1V导致一个有四个受影响小男孩的家庭中出现Borjeson-Forsman-Lehmann综合征。分子综合征SCI升级版医学4区SCI基础版医学4区IF 0.9
Ernst A, Le VQ, Højland AT, Pedersen IS, Sørensen TH, Bjerregaard LL, Lyngbye TJ, Gammelager NM, Krarup H, Petersen MB. Ernst A, et al. Mol Syndromol. 2015 Oct;6(4):181-6. doi: 10.1159/000441047. Epub 2015 Sep 29. Mol Syndromol. 2015. PMID: 26648834 Free PMC article.
PHF6 Degrees of Separation: The Multifaceted Roles of a Chromatin Adaptor Protein. GenesSCI升级版 生物学3区SCI基础版 生物3区IF 2.8
PHF 6分离度：染色质适配器蛋白的多方面作用。GenesSCI升级版生物学3区SCI基础版生物3区IF 2.8
Todd MA, Ivanochko D, Picketts DJ. Todd MA, et al. Genes (Basel). 2015 Jun 19;6(2):325-52. doi: 10.3390/genes6020325. Genes (Basel). 2015. PMID: 26103525 Free PMC article. Review.
Tau assembly: the dominant role of PHF6 (VQIVYK) in microtubule binding region repeat R3. Journal of Physical Chemistry bEI检索SCI升级版 化学2区SCI基础版 化学3区IF 2.8
Tau组装：PHF 6（VQIVGK）在微小管结合区重复R3中的主导作用。Journal of Physical Chemistry bEI检测数据库SCI升级版化学2区SCI基础版化学3区IF 2.8
Ganguly P, Do TD, Larini L, LaPointe NE, Sercel AJ, Shade MF, Feinstein SC, Bowers MT, Shea JE. Ganguly P, et al. J Phys Chem B. 2015 Apr 2;119(13):4582-93. doi: 10.1021/acs.jpcb.5b00175. Epub 2015 Mar 24. J Phys Chem B. 2015. PMID: 25775228 Free PMC article.
A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth. Genes & Development生物学TOPSCI升级版 生物学1区SCI基础版 生物1区IF 7.5
基因组规模的体内功能丧失筛查确定Phf6是白血病细胞生长的谱系特异性调节因子。基因与发育生物学TOPSCI升级版生物学1区SCI基础版生物1区IF 7.5
Meacham CE, Lawton LN, Soto-Feliciano YM, Pritchard JR, Joughin BA, Ehrenberger T, Fenouille N, Zuber J, Williams RT, Young RA, Hemann MT. Meacham CE, et al. Genes Dev. 2015 Mar 1;29(5):483-8. doi: 10.1101/gad.254151.114. Genes Dev. 2015. PMID: 25737277 Free PMC article.
Structural basis of plant homeodomain finger 6 (PHF6) recognition by the retinoblastoma binding protein 4 (RBBP4) component of the nucleosome remodeling and deacetylase (NuRD) complex. The Journal of Biological Chemistry生物学TOPEI检索SCI升级版 生物学2区SCI基础版 生物2区IF 4.0
核三体重塑和脱乙基酶（NuRD）复合物的视网膜母细胞瘤结合蛋白4（RBBP 4）成分识别植物同源结构域手指6（PHF 6）的结构基础。The Journal of Biological Chemistry生物学TOPe检查SCI升级版生物学2区SCI基础版生物2区IF 4.0
Liu Z, Li F, Zhang B, Li S, Wu J, Shi Y. Liu Z, et al. J Biol Chem. 2015 Mar 6;290(10):6630-8. doi: 10.1074/jbc.M114.610196. Epub 2015 Jan 19. J Biol Chem. 2015. PMID: 25601084 Free PMC article.
miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6. Elife生物学TOPSCI升级版 生物学1区SCI基础版 生物2区IF 6.4
MIR-128通过智能障碍基因Phf6调节神经元的迁移、突起和内在兴奋性。ELife生物学TOPSCI升级版生物学1区SCI基础版生物2区IF 6.4
Franzoni E, Booker SA, Parthasarathy S, Rehfeld F, Grosser S, Srivatsa S, Fuchs HR, Tarabykin V, Vida I, Wulczyn FG. Franzoni E, et al. Elife. 2015 Jan 3;4:e04263. doi: 10.7554/eLife.04263. Elife. 2015. PMID: 25556700 Free PMC article.
MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia. Haematologica医学TOPSCI升级版 医学1区SCI基础版 医学1区IF 8.2
MicroRNA-128-3p是针对PHF6治疗T细胞急性淋巴细胞白血病的一种新的肿瘤标志物。血液学医学TOPSCI升级版医学1区SCI基础版医学1区IF 8.2
Mets E, Van Peer G, Van der Meulen J, Boice M, Taghon T, Goossens S, Mestdagh P, Benoit Y, De Moerloose B, Van Roy N, Poppe B, Vandesompele J, Wendel HG, Van Vlierberghe P, Speleman F, Rondou P. Mets E, et al. Haematologica. 2014 Aug;99(8):1326-33. doi: 10.3324/haematol.2013.099515. Epub 2014 Jun 3. Haematologica. 2014. PMID: 24895337 Free PMC article.
Structural and functional insights into the human Borjeson-Forssman-Lehmann syndrome-associated protein PHF6. The Journal of Biological Chemistry生物学TOPEI检索SCI升级版 生物学2区SCI基础版 生物2区IF 4.0
人类Borjeson-Forssman-Lehmann综合征相关蛋白PHF 6的结构和功能见解。The Journal of Biological Chemistry生物学TOPe检查SCI升级版生物学2区SCI基础版生物2区IF 4.0
Liu Z, Li F, Ruan K, Zhang J, Mei Y, Wu J, Shi Y. Liu Z, et al. J Biol Chem. 2014 Apr 4;289(14):10069-83. doi: 10.1074/jbc.M113.535351. Epub 2014 Feb 19. J Biol Chem. 2014. PMID: 24554700 Free PMC article.
The X-linked intellectual disability protein PHF6 associates with the PAF1 complex and regulates neuronal migration in the mammalian brain. Neuron医学TOPSCI升级版 医学1区SCI基础版 医学1区IF 14.7
X连锁的智能障碍蛋白PHF6与PAF1复合体相关，并调节哺乳动物大脑中的神经元迁移。神经元医学TOPSCI升级版医学1区SCI基础版医学1区IF 14.7
Zhang C, Mejia LA, Huang J, Valnegri P, Bennett EJ, Anckar J, Jahani-Asl A, Gallardo G, Ikeuchi Y, Yamada T, Rudnicki M, Harper JW, Bonni A. Zhang C, et al. Neuron. 2013 Jun 19;78(6):986-93. doi: 10.1016/j.neuron.2013.04.021. Neuron. 2013. PMID: 23791194 Free PMC article.
PHF6 regulates cell cycle progression by suppressing ribosomal RNA synthesis. The Journal of Biological Chemistry生物学TOPEI检索SCI升级版 生物学2区SCI基础版 生物2区IF 4.0
PHF6通过抑制核糖体RNA的合成来调节细胞周期进程。《生物化学杂志》生物学TOPEI检索SCI升级版生物学2区SCI基础版生物2区IF 4.0
Wang J, Leung JW, Gong Z, Feng L, Shi X, Chen J. Wang J, et al. J Biol Chem. 2013 Feb 1;288(5):3174-83. doi: 10.1074/jbc.M112.414839. Epub 2012 Dec 10. J Biol Chem. 2013. PMID: 23229552 Free PMC article.
PHF6 Deletions May Cause Borjeson-Forssman-Lehmann Syndrome in Females. Molecular SyndromologySCI升级版 医学4区SCI基础版 医学4区IF 0.9
PHF 6缺失可能导致女性出现Borjeson-Forssman-Lehmann综合征。分子综合征SCI升级版医学4区SCI基础版医学4区IF 0.9
Berland S, Alme K, Brendehaug A, Houge G, Hovland R. Berland S, et al. Mol Syndromol. 2011 Sep;1(6):294-300. doi: 10.1159/000330111. Epub 2011 Jul 19. Mol Syndromol. 2011. PMID: 22190899 Free PMC article.
Mutations of PHF6 are associated with mutations of NOTCH1, JAK1 and rearrangement of SET-NUP214 in T-cell acute lymphoblastic leukemia. Haematologica医学TOPSCI升级版 医学1区SCI基础版 医学1区IF 8.2
PHF6基因突变与T细胞急性淋巴细胞白血病的NOTCH1、JAK1突变和SET-NUP214重排相关。血液学医学TOPSCI升级版医学1区SCI基础版医学1区IF 8.2
Wang Q, Qiu H, Jiang H, Wu L, Dong S, Pan J, Wang W, Ping N, Xia J, Sun A, Wu D, Xue Y, Drexler HG, Macleod RA, Chen S. Wang Q, et al. Haematologica. 2011 Dec;96(12):1808-14. doi: 10.3324/haematol.2011.043083. Epub 2011 Aug 31. Haematologica. 2011. PMID: 21880637 Free PMC article. Clinical Trial.
PHF6 mutations in adult acute myeloid leukemia. Leukemia医学TOPSCI升级版 医学1区SCI基础版 医学1区IF 12.8
成人急性粒细胞白血病中的PHF 6突变。Leukemia医学TOPSCI升级版医学1区SCI基础版医学1区IF 12.8
Van Vlierberghe P, Patel J, Abdel-Wahab O, Lobry C, Hedvat CV, Balbin M, Nicolas C, Payer AR, Fernandez HF, Tallman MS, Paietta E, Melnick A, Vandenberghe P, Speleman F, Aifantis I, Cools J, Levine R, Ferrando A. Van Vlierberghe P, et al. Leukemia. 2011 Jan;25(1):130-4. doi: 10.1038/leu.2010.247. Epub 2010 Oct 29. Leukemia. 2011. PMID: 21030981 Free PMC article.
T-cell acute lymphoblastic leukemia in association with Borjeson-Forssman-Lehmann syndrome due to a mutation in PHF6. Pediatric Blood & CancerSCI升级版 医学3区SCI基础版 医学3区IF 2.4
PHF 6突变导致T细胞急性淋巴细胞白血病与Borjeson-Forssman-Lehmann综合征相关。Pediatric Blood & CancerSCI升级版医学3区SCI基础版医学3区IF 2.4
Chao MM, Todd MA, Kontny U, Neas K, Sullivan MJ, Hunter AG, Picketts DJ, Kratz CP. Chao MM, et al. Pediatr Blood Cancer. 2010 Oct;55(4):722-4. doi: 10.1002/pbc.22574. Pediatr Blood Cancer. 2010. PMID: 20806366 Free PMC article.
PHF6 mutations in T-cell acute lymphoblastic leukemia. Nature Genetics生物学TOPSCI升级版 生物学1区SCI基础版 生物1区IF 31.7
T细胞急性淋巴细胞白血病PHF6基因突变的研究自然遗传学生物学TOPSCI升级版生物学1区SCI基础版生物1区IF 31.7.
Van Vlierberghe P, Palomero T, Khiabanian H, Van der Meulen J, Castillo M, Van Roy N, De Moerloose B, Philippé J, González-García S, Toribio ML, Taghon T, Zuurbier L, Cauwelier B, Harrison CJ, Schwab C, Pisecker M, Strehl S, Langerak AW, Gecz J, Sonneveld E, Pieters R, Paietta E, Rowe JM, Wiernik PH, Benoit Y, Soulier J, Poppe B, Yao X, Cordon-Cardo C, Meijerink J, Rabadan R, Speleman F, Ferrando A. Van Vlierberghe P, et al. Nat Genet. 2010 Apr;42(4):338-42. doi: 10.1038/ng.542. Epub 2010 Mar 14. Nat Genet. 2010. PMID: 20228800 Free PMC article.
Conformational sampling with implicit solvent models: application to the PHF6 peptide in tau protein. Biophysical JournalSCI升级版 生物学3区SCI基础版 生物3区IF 3.2
采用隐式溶剂模型的形态采样：应用于tau蛋白中的PHF 6肽。Biophysical JournalSCI升级版生物学3区SCI基础版生物3区IF 3.2
Huang A, Stultz CM. Huang A, et al. Biophys J. 2007 Jan 1;92(1):34-45. doi: 10.1529/biophysj.106.091207. Epub 2006 Oct 13. Biophys J. 2007. PMID: 17040986 Free PMC article.
Radiation leukemia virus common integration at the Kis2 locus: simultaneous overexpression of a novel noncoding RNA and of the proximal Phf6 gene. Journal of Virology医学TOPSCI升级版 医学2区SCI基础版 医学2区IF 4.0
放射性白血病病毒在Kis 2基因座的共同整合：新型非编码RNA和近端Phf 6基因的同时过度表达。Journal of Virology医学TOPSCI升级版医学2区SCI基础版医学2区IF 4.0
Landais S, Quantin R, Rassart E. Landais S, et al. J Virol. 2005 Sep;79(17):11443-56. doi: 10.1128/JVI.79.17.11443-11456.2005. J Virol. 2005. PMID: 16103195 Free PMC article.
Mutation screening in Borjeson-Forssman-Lehmann syndrome: identification of a novel de novo PHF6 mutation in a female patient. Journal of Medical GeneticsSCI升级版 医学2区SCI基础版 医学2区IF 3.5
Borjeson-Forssman-Lehmann综合征的突变筛查：在女性患者中鉴定出一种新型从头PHF 6突变。Journal of Medical Genetics SCI升级版医学2区SCI基础版医学2区IF 3.5
Crawford J, Lower KM, Hennekam RC, Van Esch H, Mégarbané A, Lynch SA, Turner G, Gécz J. Crawford J, et al. J Med Genet. 2006 Mar;43(3):238-43. doi: 10.1136/jmg.2005.033084. Epub 2005 Jul 1. J Med Genet. 2006. PMID: 15994862 Free PMC article.
A novel PHF6 mutation results in enhanced exon skipping and mild Borjeson-Forssman-Lehmann syndrome. Journal of Medical GeneticsSCI升级版 医学2区SCI基础版 医学2区IF 3.5
一种新的PHF 6突变导致增强的exon跳读和轻度Borjeson-Forssman-Lehmann综合征。Journal of Medical Genetics SCI升级版医学2区SCI基础版医学2区IF 3.5
Vallée D, Chevrier E, Graham GE, Lazzaro MA, Lavigne PA, Hunter AG, Picketts DJ. Vallée D, et al. J Med Genet. 2004 Oct;41(10):778-83. doi: 10.1136/jmg.2004.020370. J Med Genet. 2004. PMID: 15466013 Free PMC article. No abstract available.
Novel PHF6 mutation p.D333del causes Borjeson-Forssman-Lehmann syndrome. Journal of Medical GeneticsSCI升级版 医学2区SCI基础版 医学2区IF 3.5
新型PHF 6突变p.D333del导致Borjeson-Forssman-Lehmann综合征。Journal of Medical Genetics SCI升级版医学2区SCI基础版医学2区IF 3.5
Baumstark A, Lower KM, Sinkus A, Andriuskeviciute I, Jurkeniene L, Gécz J, Just W. Baumstark A, et al. J Med Genet. 2003 Apr;40(4):e50. doi: 10.1136/jmg.40.4.e50. J Med Genet. 2003. PMID: 12676923 Free PMC article. No abstract available.
Cite
75 results  75个结果